Distinct Regulatory Mechanisms Govern Embryonic versus Adult Adipocyte Maturation

Pathological expansion of adipose tissue contributes to the metabolic syndrome. Distinct depots develop at various times under different physiological conditions. The transcriptional cascade mediating adipogenesis is established in vitro, and centers around a core program involving PPARγ and C/EBPα....

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Udgivet i:Nat Cell Biol
Main Authors: Wang, Qiong A., Tao, Caroline, Jiang, Lei, Shao, Mengle, Ye, Risheng, Zhu, Yi, Gordillo, Ruth, Ali, Aktar, Lian, Yun, Holland, William L., Gupta, Rana K., Scherer, Philipp E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4553131/
https://ncbi.nlm.nih.gov/pubmed/26280538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3217
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