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New perspectives for targeting RAF kinase in human cancer
The discovery that a subset of human tumours is dependent on mutationally deregulated BRAF kinase intensified the development of RAF inhibitors to be used as potential therapeutics. The US Food and Drug Administration (FDA)-approved second-generation RAF inhibitors vemurafenib and dabrafenib have el...
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| Pubblicato in: | Nat Rev Cancer |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6000833/ https://ncbi.nlm.nih.gov/pubmed/28984291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc.2017.79 |
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