Progestin and AdipoQ Receptor 3 Upregulates Fibronectin and Intercellular Adhesion Molecule-1 in Glomerular Mesangial Cells via Activating NF-κB Signaling Pathway Under High Glucose Conditions

BACKGROUND: Progestin and adipoQ receptor 3 (PAQR3), is a Golgi-anchored membrane protein containing seven transmembrane helices. It has been demonstrated that PAQR3 mediates insulin resistance, glucose and lipid metabolism, and inflammation. In addition, kidney inflammatory fibrosis is an important...

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Foilsithe in:Front Endocrinol (Lausanne)
Main Authors: Zou, Yezi, Chen, Zhiquan, Li, Jie, Gong, Wenyan, Zhang, Lei, Xu, Futian, Chen, Lihao, Liu, Peiqing, Huang, Heqing
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Endocrinology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5999916/
https://ncbi.nlm.nih.gov/pubmed/29930535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00275
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