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Apoptosis and signalling in acid sphingomyelinase deficient cells

BACKGROUND: Recent evidence suggests that the activation of a non-specific lipid scramblase during apoptosis induces the flipping of sphingomyelin from the cell surface to the cytoplasmic leaftet of the plasma membrane. Inner leaflet sphingomyelin is then cleaved to ceramide by a neutral sphingomyel...

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Detalhes bibliográficos
Autor principal: Sillence, Dan J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC59997/
https://ncbi.nlm.nih.gov/pubmed/11722792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-2-24
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