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Involvement of the Acid Sphingomyelinase Pathway in UVA-induced Apoptosis

The sphingomyelin-ceramide pathway is an evolutionarily conserved ubiquitous signal transduction system that regulates many cell functions including apoptosis. Sphingomyelin (SM) is hydrolyzed to ceramide by different sphingomyelinases. Ceramide serves as a second messenger in mediating cellular eff...

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Detalhes bibliográficos
Main Authors: Zhang, Yiguo, Mattjus, Peter, Schmid, Patricia C., Dong, Ziming, Zhong, Shuping, Ma, Wei-Ya, Brown, Rhoderick E., Bode, Ann M., Schmid, Harald H. O., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621016/
https://ncbi.nlm.nih.gov/pubmed/11278294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M006000200
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