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Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly

Protein–protein interactions critically regulate many biological systems, but quantifying functional assembly of multipass membrane complexes in their native context is still challenging. Here, we combined modeling-assisted protein modification and information from human disease variants with a mini...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: O'Neill, Sharon, Mathis, Magalie, Kovačič, Lidija, Zhang, Suisheng, Reinhardt, Jürgen, Scholz, Dimitri, Schopfer, Ulrich, Bouhelal, Rochdi, Knaus, Ulla G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995528/
https://ncbi.nlm.nih.gov/pubmed/29674345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001045
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