The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

In contrast to the NADPH oxidases Nox1 and Nox2, which generate superoxide (O(2)(˙̄)), Nox4 produces hydrogen peroxide (H(2)O(2)). We constructed chimeric proteins and mutants to address the protein region that specifies which reactive oxygen species is produced. Reactive oxygen species were measure...

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Detalhes bibliográficos
Main Authors: Takac, Ina, Schröder, Katrin, Zhang, Leilei, Lardy, Bernard, Anilkumar, Narayana, Lambeth, J. David, Shah, Ajay M., Morel, Francoise, Brandes, Ralf P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075677/
https://ncbi.nlm.nih.gov/pubmed/21343298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192138
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