Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly

Protein–protein interactions critically regulate many biological systems, but quantifying functional assembly of multipass membrane complexes in their native context is still challenging. Here, we combined modeling-assisted protein modification and information from human disease variants with a mini...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: O'Neill, Sharon, Mathis, Magalie, Kovačič, Lidija, Zhang, Suisheng, Reinhardt, Jürgen, Scholz, Dimitri, Schopfer, Ulrich, Bouhelal, Rochdi, Knaus, Ulla G.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Enzymology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995528/
https://ncbi.nlm.nih.gov/pubmed/29674345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001045
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