Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly

Protein–protein interactions critically regulate many biological systems, but quantifying functional assembly of multipass membrane complexes in their native context is still challenging. Here, we combined modeling-assisted protein modification and information from human disease variants with a mini...

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Vydáno v:J Biol Chem
Hlavní autoři: O'Neill, Sharon, Mathis, Magalie, Kovačič, Lidija, Zhang, Suisheng, Reinhardt, Jürgen, Scholz, Dimitri, Schopfer, Ulrich, Bouhelal, Rochdi, Knaus, Ulla G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995528/
https://ncbi.nlm.nih.gov/pubmed/29674345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001045
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