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Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins

Cotranslational protein folding can facilitate rapid formation of functional structures. However, it might also cause premature assembly of protein complexes, if two interacting nascent chains are in close proximity. By analyzing known protein structures, we show that homomeric protein contacts are...

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書誌詳細
出版年:Nat Struct Mol Biol
主要な著者: Natan, Eviatar, Endoh, Tamaki, Haim-Vilmovsky, Liora, Flock, Tilman, Chalancon, Guilhem, Hopper, Jonathan TS., Kintses, Bálint, Horvath, Peter, Daruka, Lejla, Fekete, Gergely, Pál, Csaba, Papp, Balázs, Őszi, Erika, Magyar, Zoltán, Marsh, Joseph A., Elcock, Adrian H., Babu, M Madan, Robinson, Carol V., Sugimoto, Naoki, Teichmann, Sarah A.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995306/
https://ncbi.nlm.nih.gov/pubmed/29434345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0029-5
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