Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia

BACKGROUND: Chronic myeloid leukemia (CML) results from hematopoietic stem cell transformation by the bcr-abl chimeric oncogene, encoding a 210 kDa protein with constitutive tyrosine kinase activity. In spite of the efficiency of tyrosine kinase inhibitors (TKI; Imatinib), other strategies are explo...

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Publicat a:Oncotarget
Autors principals: Cabanas, Hélène, Harnois, Thomas, Magaud, Christophe, Cousin, Laëtitia, Constantin, Bruno, Bourmeyster, Nicolas, Déliot, Nadine
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995172/
https://ncbi.nlm.nih.gov/pubmed/29899861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25241
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