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Deregulated expression of Cdc6 as BCR/ABL-dependent survival factor in chronic myeloid leukemia cells

Chronic myeloid leukemia is characterized by the presence of the reciprocal translocation t(9;22) and the BCR/ABL oncogene. The BCR/ABL oncogene activates multiple signaling pathways and involves the dysregulation of oncogenes during the progression of chronic myeloid leukemia. The cell division cyc...

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Bibliografiske detaljer
Main Authors: Jia-Hua Zhang, Yan-Li He, Rui Zhu, Wen Du, Jun-Hua Xiao
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2017-06-01
Serier:Tumor Biology
Online adgang:https://doi.org/10.1177/1010428317713394
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