Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells

Antitumor chemotherapy remains one of the most important challenge of the medicinal chemistry. Emerging research in chemotherapy is focused on exploiting the biochemical differences between cancer cell and normal cell metabolism in order to reduce the side effects and increase antitumor therapy effi...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Gazzano, Elena, Lazzarato, Loretta, Rolando, Barbara, Kopecka, Joanna, Guglielmo, Stefano, Costamagna, Costanzo, Chegaev, Konstantin, Riganti, Chiara
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994430/
https://ncbi.nlm.nih.gov/pubmed/29915539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00580
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