Mitochondrial Delivery of Phenol Substructure Triggers Mitochondrial Depolarization and Apoptosis of Cancer Cells

Antitumor chemotherapy remains one of the most important challenge of the medicinal chemistry. Emerging research in chemotherapy is focused on exploiting the biochemical differences between cancer cell and normal cell metabolism in order to reduce the side effects and increase antitumor therapy effi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Gazzano, Elena, Lazzarato, Loretta, Rolando, Barbara, Kopecka, Joanna, Guglielmo, Stefano, Costamagna, Costanzo, Chegaev, Konstantin, Riganti, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994430/
https://ncbi.nlm.nih.gov/pubmed/29915539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00580
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