Nitric Oxide Donor Doxorubicins Accumulate into Doxorubicin-Resistant Human Colon Cancer Cells Inducing Cytotoxicity

[Image: see text] Products 4 and 5, obtained by conjugation of doxorubicin with nitric oxide (NO) donor nitrooxy and phenylsulfonyl furoxan moieties, respectively, accumulate in doxorubicin-resistant human colon cancer cells (HT29-dx), inducing high cytotoxicity. This behavior parallels the ability...

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Detalhes bibliográficos
Main Authors: Chegaev, Konstantin, Riganti, Chiara, Lazzarato, Loretta, Rolando, Barbara, Guglielmo, Stefano, Campia, Ivana, Fruttero, Roberta, Bosia, Amalia, Gasco, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018161/
https://ncbi.nlm.nih.gov/pubmed/24900337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100302t
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