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Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks
The RNA-guided DNA endonuclease Cas9 is a powerful tool for genome editing. Little is known about the kinetics and fidelity of the double-strand break (DSB) repair process that follows a Cas9 cutting event in living cells. Here, we developed a strategy to measure the kinetics of DSB repair for singl...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993873/ https://ncbi.nlm.nih.gov/pubmed/29804829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.016 |
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