Measuring the global substrate specificity of mycobacterial serine hydrolases using a library of fluorogenic ester substrates

Among the proteins required for lipid metabolism in M. tuberculosis are a significant number of uncharacterized serine hydrolases, especially lipases and esterases. Using a streamlined synthetic method, a library of immolative fluorogenic ester substrates were expanded to better represent the natura...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Infect Dis
Main Authors: Bassett, Braden, Waibel, Brent, White, Alex, Hansen, Heather, Stephens, Dominique, Koelper, Andrew, Larsen, Erik M., Kim, Charles, Glanzer, Adam, Lavis, Luke D., Hoops, Geoffrey C., Johnson, R. Jeremy
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993602/
https://ncbi.nlm.nih.gov/pubmed/29648787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00263
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki