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Measuring the global substrate specificity of mycobacterial serine hydrolases using a library of fluorogenic ester substrates
Among the proteins required for lipid metabolism in M. tuberculosis are a significant number of uncharacterized serine hydrolases, especially lipases and esterases. Using a streamlined synthetic method, a library of immolative fluorogenic ester substrates were expanded to better represent the natura...
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| Publicado no: | ACS Infect Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993602/ https://ncbi.nlm.nih.gov/pubmed/29648787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00263 |
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