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Differential strengths of molecular determinants guide environment specific mutational fates
Organisms maintain competitive fitness in the face of environmental challenges through molecular evolution. However, it remains largely unknown how different biophysical factors constrain molecular evolution in a given environment. Here, using deep mutational scanning, we quantified empirical fitnes...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5993328/ https://ncbi.nlm.nih.gov/pubmed/29813059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007419 |
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