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Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer

Cancer cells often upregulate nutrient transporters to fulfill their increased biosynthetic and bioenergetic needs, and to maintain redox homeostasis. One nutrient transporter frequently overexpressed in human cancers is the cystine/glutamate antiporter solute carrier family 7 member 11 (SLC7A11; al...

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Dettagli Bibliografici
Pubblicato in:Cancer Commun (Lond)
Autori principali: Koppula, Pranavi, Zhang, Yilei, Zhuang, Li, Gan, Boyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993148/
https://ncbi.nlm.nih.gov/pubmed/29764521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-018-0288-x
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