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Comprehensive Analysis of the Unfolded Protein Response in Breast Cancer Subtypes

PURPOSE: Triple-negative breast cancers (TNBCs) are associated with a worse prognosis and patients with TNBC have fewer therapeutic options than patients with non-TNBC. Recently, the IRE1α-XBP1 branch of the unfolded protein response (UPR) was implicated in TNBC prognosis on the basis of a relativel...

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Bibliographic Details
Published in:JCO Precis Oncol
Main Authors: Jiang, Dadi, Turner, Brandon, Song, Jie, Li, Ruijiang, Diehn, Maximilian, Le, Quynh-Thu, Khatri, Purvesh, Koong, Albert C.
Format: Artigo
Language:Inglês
Published: American Society of Clinical Oncology 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992919/
https://ncbi.nlm.nih.gov/pubmed/29888341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.16.00073
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