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Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity

Malformations of the intrahepatic biliary structure cause cholestasis, a liver pathology that corresponds to poor bile flow, which leads to inflammation, fibrosis, and cirrhosis. Although the specification of biliary epithelial cells (BECs) that line the bile ducts is fairly well understood, the mol...

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Dettagli Bibliografici
Pubblicato in:Hepatology
Autori principali: So, Juhoon, Khaliq, Mehwish, Evason, Kimberley, Ninov, Nikolay, Martin, Benjamin L., Stainier, Didier Y.R., Shin, Donghun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991997/
https://ncbi.nlm.nih.gov/pubmed/29266316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29752
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