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Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity

Malformations of the intrahepatic biliary structure cause cholestasis, a liver pathology that corresponds to poor bile flow, which leads to inflammation, fibrosis, and cirrhosis. Although the specification of biliary epithelial cells (BECs) that line the bile ducts is fairly well understood, the mol...

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Bibliografiska uppgifter
I publikationen:Hepatology
Huvudupphovsmän: So, Juhoon, Khaliq, Mehwish, Evason, Kimberley, Ninov, Nikolay, Martin, Benjamin L., Stainier, Didier Y.R., Shin, Donghun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991997/
https://ncbi.nlm.nih.gov/pubmed/29266316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29752
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