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Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity

Malformations of the intrahepatic biliary structure cause cholestasis, a liver pathology that corresponds to poor bile flow, which leads to inflammation, fibrosis, and cirrhosis. Although the specification of biliary epithelial cells (BECs) that line the bile ducts is fairly well understood, the mol...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: So, Juhoon, Khaliq, Mehwish, Evason, Kimberley, Ninov, Nikolay, Martin, Benjamin L., Stainier, Didier Y.R., Shin, Donghun
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991997/
https://ncbi.nlm.nih.gov/pubmed/29266316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29752
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