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Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity

Malformations of the intrahepatic biliary structure cause cholestasis, a liver pathology that corresponds to poor bile flow, which leads to inflammation, fibrosis, and cirrhosis. Although the specification of biliary epithelial cells (BECs) that line the bile ducts is fairly well understood, the mol...

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Bibliografske podrobnosti
izdano v:Hepatology
Main Authors: So, Juhoon, Khaliq, Mehwish, Evason, Kimberley, Ninov, Nikolay, Martin, Benjamin L., Stainier, Didier Y.R., Shin, Donghun
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991997/
https://ncbi.nlm.nih.gov/pubmed/29266316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29752
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