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A sex chromosome piRNA promotes robust dosage compensation and sex determination in C. elegans
In metazoans, Piwi-related Argonaute proteins engage piRNAs (Piwi-interacting small RNAs) to defend the genome against invasive nucleic acids, such as transposable elements. Yet many organisms—including worms and humans—express thousands of piRNA that do not target transposons, suggesting that piRNA...
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| Udgivet i: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5991626/ https://ncbi.nlm.nih.gov/pubmed/29456136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.01.025 |
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