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The ribonuclease PARN-1 trims piRNA 3′ ends to promote transcriptome surveillance in C. elegans

piRNAs engage Piwi proteins to suppress transposons and are essential for fertility in diverse organisms. An interesting feature of piRNAs is that, while piRNA lengths are stereotypical within a species, they can differ widely between species. For example piRNAs are mainly 29 and 30 nucleotides in h...

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Vydáno v:Cell
Hlavní autoři: Tang, Wen, Tu, Shikui, Lee, Heng-Chi, Weng, Zhiping, Mello, Craig C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785802/
https://ncbi.nlm.nih.gov/pubmed/26919432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.008
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