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Mutations close to a hub residue affect the distant active site of a GH1 β-glucosidase
The tertiary structure of proteins has been represented as a network, in which residues are nodes and their contacts are edges. Protein structure networks contain residues, called hubs or central, which are essential to form short connection pathways between any pair of nodes. Hence hub residues may...
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| Published in: | PLoS One |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5991390/ https://ncbi.nlm.nih.gov/pubmed/29874288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198696 |
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