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Mutations close to a hub residue affect the distant active site of a GH1 β-glucosidase

The tertiary structure of proteins has been represented as a network, in which residues are nodes and their contacts are edges. Protein structure networks contain residues, called hubs or central, which are essential to form short connection pathways between any pair of nodes. Hence hub residues may...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Souza, Valquiria P., Ikegami, Cecília M., Arantes, Guilherme M., Marana, Sandro R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991390/
https://ncbi.nlm.nih.gov/pubmed/29874288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198696
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