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Mutations close to a hub residue affect the distant active site of a GH1 β-glucosidase

The tertiary structure of proteins has been represented as a network, in which residues are nodes and their contacts are edges. Protein structure networks contain residues, called hubs or central, which are essential to form short connection pathways between any pair of nodes. Hence hub residues may...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Souza, Valquiria P., Ikegami, Cecília M., Arantes, Guilherme M., Marana, Sandro R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991390/
https://ncbi.nlm.nih.gov/pubmed/29874288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198696
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