Cues to Opening Mechanisms From in Silico Electric Field Excitation of Cx26 Hemichannel and in Vitro Mutagenesis Studies in HeLa Transfectans

Connexin channels play numerous essential roles in virtually every organ by mediating solute exchange between adjacent cells, or between cytoplasm and extracellular milieu. Our understanding of the structure-function relationship of connexin channels relies on X-ray crystallographic data for human c...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Zonta, Francesco, Buratto, Damiano, Crispino, Giulia, Carrer, Andrea, Bruno, Francesca, Yang, Guang, Mammano, Fabio, Pantano, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990870/
https://ncbi.nlm.nih.gov/pubmed/29904340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00170
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