Cues to Opening Mechanisms From in Silico Electric Field Excitation of Cx26 Hemichannel and in Vitro Mutagenesis Studies in HeLa Transfectans

Connexin channels play numerous essential roles in virtually every organ by mediating solute exchange between adjacent cells, or between cytoplasm and extracellular milieu. Our understanding of the structure-function relationship of connexin channels relies on X-ray crystallographic data for human c...

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Dettagli Bibliografici
Pubblicato in:Front Mol Neurosci
Autori principali: Zonta, Francesco, Buratto, Damiano, Crispino, Giulia, Carrer, Andrea, Bruno, Francesca, Yang, Guang, Mammano, Fabio, Pantano, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990870/
https://ncbi.nlm.nih.gov/pubmed/29904340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00170
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