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CpG Island Methylator Phenotype and Methylation of Wnt Pathway Genes Together Predict Survival in Patients with Colorectal Cancer

PURPOSE: Dysregulation of the Wnt pathway is a crucial step in the tumorigenesis of colorectal cancer (CRC). This study aimed to determine whether DNA methylation of Wnt pathway genes helps predict treatment response and survival in patients with metastatic or recurrent CRC. MATERIALS AND METHODS: W...

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Detalhes bibliográficos
Publicado no:Yonsei Med J
Main Authors: Kim, Se Hyun, Park, Kyu Hyun, Shin, Sang Joon, Lee, Kang Young, Kim, Tae Il, Kim, Nam Kyu, Rha, Sun Young, Ahn, Joong Bae
Formato: Artigo
Idioma:Inglês
Publicado em: Yonsei University College of Medicine 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990680/
https://ncbi.nlm.nih.gov/pubmed/29869456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2018.59.5.588
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