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Adverse prognostic impact of the CpG island methylator phenotype in metastatic colorectal cancer

BACKGROUND: The association between the CpG island methylator phenotype (CIMP) and clinical outcomes in metastatic colorectal cancer remains unclear. We investigated the prognostic impact of CIMP in patients with metastatic colorectal cancer treated with systemic chemotherapy. METHODS: Eight CIMP-sp...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Cha, Yongjun, Kim, Kyung-Ju, Han, Sae-Won, Rhee, Ye Young, Bae, Jeong Mo, Wen, Xianyu, Cho, Nam-Yun, Lee, Dae-Won, Lee, Kyung-Hun, Kim, Tae-Yong, Oh, Do-Youn, Im, Seock-Ah, Bang, Yung-Jue, Jeong, Seung-Yong, Park, Kyu Joo, Kang, Gyeong Hoon, Kim, Tae-You
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947699/
https://ncbi.nlm.nih.gov/pubmed/27310704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.176
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