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Adverse prognostic impact of the CpG island methylator phenotype in metastatic colorectal cancer

BACKGROUND: The association between the CpG island methylator phenotype (CIMP) and clinical outcomes in metastatic colorectal cancer remains unclear. We investigated the prognostic impact of CIMP in patients with metastatic colorectal cancer treated with systemic chemotherapy. METHODS: Eight CIMP-sp...

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Pubblicato in:Br J Cancer
Autori principali: Cha, Yongjun, Kim, Kyung-Ju, Han, Sae-Won, Rhee, Ye Young, Bae, Jeong Mo, Wen, Xianyu, Cho, Nam-Yun, Lee, Dae-Won, Lee, Kyung-Hun, Kim, Tae-Yong, Oh, Do-Youn, Im, Seock-Ah, Bang, Yung-Jue, Jeong, Seung-Yong, Park, Kyu Joo, Kang, Gyeong Hoon, Kim, Tae-You
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947699/
https://ncbi.nlm.nih.gov/pubmed/27310704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.176
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