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An Intermediate Pluripotent State Controlled by microRNAs is Required for the Naïve to Primed Stem Cell Transition
The embryonic stem cell (ESC) transition from naive to primed pluripotency is marked by major changes in cellular properties and developmental potential. ISY1 regulates miRNA biogenesis yet its role and relevance to ESC biology remain unknown. Here we find that highly dynamic ISY1 expression during...
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| Udgivet i: | Cell Stem Cell |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5990487/ https://ncbi.nlm.nih.gov/pubmed/29804889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.04.021 |
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