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Single-molecule FRET reveals proofreading complexes in the large fragment of Bacillus stearothermophilus DNA polymerase I

There is increasing interest in the use of DNA polymerases (DNA pols) in next-generation sequencing strategies. These methodologies typically rely on members of the A and B family of DNA polymerases that are classified as high-fidelity DNA polymerases. These enzymes possess the ability to selectivel...

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Vydáno v:AIMS Biophys
Hlavní autoři: Christian, Thomas V., Konigsberg, William H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990039/
https://ncbi.nlm.nih.gov/pubmed/29888335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/biophy.2018.2.144
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