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Single-Molecule FRET Reveals Hidden Complexity in a Protein Energy Landscape
Here, using single-molecule FRET, we reveal previously hidden conformations of the ankyrin-repeat domain of AnkyrinR, a giant adaptor molecule that anchors integral membrane proteins to the spectrin-actin cytoskeleton through simultaneous binding of multiple partner proteins. We show that the ankyri...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4291146/ https://ncbi.nlm.nih.gov/pubmed/25565106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.10.023 |
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