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Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire

Eliciting broad and potent HIV-specific neutralizing antibody responses represents the holy grail of HIV vaccine efforts. Data from singly infected individuals with broad and potent plasma neutralizing activity targeting one epitope have guided our understanding of how these responses develop. Howev...

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Publicado en:Cell Rep
Main Authors: Williams, Katherine L., Wang, Bingjie, Arenz, Dana, Williams, James A., Dingens, Adam S., Cortez, Valerie, Simonich, Cassandra A., Rainwater, Stephanie, Lehman, Dara A., Lee, Kelly K., Overbaugh, Julie
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990032/
https://ncbi.nlm.nih.gov/pubmed/29669274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.082
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