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An antigenic atlas of HIV-1 escape from broadly neutralizing antibodies distinguishes functional and structural epitopes

Anti-HIV broadly neutralizing antibodies (bnAbs) have revealed vaccine targets on the virus’s envelope (Env) protein and are themselves promising immunotherapeutics. The efficacy of bnAb-based therapies and vaccines depends in part on how readily the virus can escape neutralization. While structural...

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Bibliographic Details
Published in:Immunity
Main Authors: Dingens, Adam S., Arenz, Dana, Weight, Haidyn, Overbaugh, Julie, Bloom, Jesse D.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435357/
https://ncbi.nlm.nih.gov/pubmed/30709739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.12.017
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