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An antigenic atlas of HIV-1 escape from broadly neutralizing antibodies distinguishes functional and structural epitopes

Anti-HIV broadly neutralizing antibodies (bnAbs) have revealed vaccine targets on the virus’s envelope (Env) protein and are themselves promising immunotherapeutics. The efficacy of bnAb-based therapies and vaccines depends in part on how readily the virus can escape neutralization. While structural...

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Podrobná bibliografie
Vydáno v:Immunity
Hlavní autoři: Dingens, Adam S., Arenz, Dana, Weight, Haidyn, Overbaugh, Julie, Bloom, Jesse D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435357/
https://ncbi.nlm.nih.gov/pubmed/30709739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.12.017
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