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What is hydroxynorketamine and what can it bring to neurotherapeutics?
(R,S)-Ketamine was initially developed as an anesthetic agent and its pharmacological properties were determined on the basis of this clinical use. However, pharmacological studies in rat led to the development of the ‘Ketamine Paradigm’, whereby (R,S)-ketamine and its N-demethylated metabolite (R,S...
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| Опубликовано в: : | Expert Rev Neurother |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5990010/ https://ncbi.nlm.nih.gov/pubmed/25331415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737175.2014.971760 |
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