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What is hydroxynorketamine and what can it bring to neurotherapeutics?

(R,S)-Ketamine was initially developed as an anesthetic agent and its pharmacological properties were determined on the basis of this clinical use. However, pharmacological studies in rat led to the development of the ‘Ketamine Paradigm’, whereby (R,S)-ketamine and its N-demethylated metabolite (R,S...

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Podrobná bibliografie
Vydáno v:Expert Rev Neurother
Hlavní autoři: Singh, Nagendra S, Zarate, Carlos A, Moaddel, Ruin, Bernier, Michel, Wainer, Irving W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990010/
https://ncbi.nlm.nih.gov/pubmed/25331415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737175.2014.971760
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