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What is hydroxynorketamine and what can it bring to neurotherapeutics?
(R,S)-Ketamine was initially developed as an anesthetic agent and its pharmacological properties were determined on the basis of this clinical use. However, pharmacological studies in rat led to the development of the ‘Ketamine Paradigm’, whereby (R,S)-ketamine and its N-demethylated metabolite (R,S...
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| Pubblicato in: | Expert Rev Neurother |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5990010/ https://ncbi.nlm.nih.gov/pubmed/25331415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737175.2014.971760 |
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