Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches

BACKGROUND: The clinical efficacy observed with inhibitors of programed cell death 1/programed cell death ligand 1 (PD-L1/PD-1) in cancer therapy has prompted studies to characterize the immune response in several tumor types, including lung cancer. However, the immunological profile of non–small ce...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Parra, Edwin R., Villalobos, Pamela, Behrens, Carmen, Jiang, Mei, Pataer, Apar, Swisher, Stephen G., William, William N., Zhang, Jiexin, Lee, Jack, Cascone, Tina, Heymach, John V., Forget, Marie-Andrée, Haymaker, Cara, Bernatchez, Chantale, Kalhor, Neda, Weissferdt, Annikka, Moran, Cesar, Zhang, Jianjun, Vaporciyan, Ara, Gibbons, Don L., Sepesi, Boris, Wistuba, Ignacio I.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989476/
https://ncbi.nlm.nih.gov/pubmed/29871672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0368-0
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