Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome

Obstructive sleep apnea (OSA) is a common disorder characterized by episodic obstruction to breathing due to upper airway collapse during sleep. Because of the episodic airway obstruction, intermittently low O(2) (hypoxia) and high CO(2) (hypercapnia) ensue. OSA has been associated with adverse card...

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Foilsithe in:mSystems
Main Authors: Tripathi, Anupriya, Melnik, Alexey V., Xue, Jin, Poulsen, Orit, Meehan, Michael J., Humphrey, Gregory, Jiang, Lingjing, Ackermann, Gail, McDonald, Daniel, Zhou, Dan, Knight, Rob, Dorrestein, Pieter C., Haddad, Gabriel G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2018
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Observation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989129/
https://ncbi.nlm.nih.gov/pubmed/29896566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00020-18
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