Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome

Obstructive sleep apnea (OSA) is a common disorder characterized by episodic obstruction to breathing due to upper airway collapse during sleep. Because of the episodic airway obstruction, intermittently low O(2) (hypoxia) and high CO(2) (hypercapnia) ensue. OSA has been associated with adverse card...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Tripathi, Anupriya, Melnik, Alexey V., Xue, Jin, Poulsen, Orit, Meehan, Michael J., Humphrey, Gregory, Jiang, Lingjing, Ackermann, Gail, McDonald, Daniel, Zhou, Dan, Knight, Rob, Dorrestein, Pieter C., Haddad, Gabriel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Observation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989129/
https://ncbi.nlm.nih.gov/pubmed/29896566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00020-18
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