Intermittent Hypoxia and Hypercapnia Accelerate Atherosclerosis, Partially via Trimethylamine-Oxide

Obstructive sleep apnea (OSA) is a common disorder characterized by intermittent hypoxia and hypercapnia (IHC) during sleep. OSA has been shown to be a risk factor for atherosclerosis, but the relation of IHC to the induction or progression of atherosclerosis is not well understood. To dissect the m...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Xue, Jin, Zhou, Dan, Poulsen, Orit, Imamura, Toshihiro, Hsiao, Yu-Hsin, Smith, Travis H., Malhotra, Atul, Dorrestein, Pieter, Knight, Rob, Haddad, Gabriel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705907/
https://ncbi.nlm.nih.gov/pubmed/28678519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0086OC
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