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The histone methyltransferase G9a is required for silencing of helper T lineage-associated genes in proliferating CD8 T cells

Helper versus cytotoxic T lineage decision in the thymus has been studied as a model for silencing of alternative lineage genes. While the transcription factor RUNX3 is required for the initiation of Cd4 silencing in developing CD8 T cells, it is unknown how silencing of Cd4 and other helper T linea...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Verbaro, Daniel J., Sakurai, Nagisa, Kim, Byungil, Shinkai, Yoichi, Egawa, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988973/
https://ncbi.nlm.nih.gov/pubmed/29720423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701700
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