Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation

Follicular helper T (Tfh) cells provide essential help for humoral immune response. Transcriptional factor Bcl6 is the master regulator for Tfh generation and is induced very early after T cell activation in a CD28-dependent manner, but how CD28 signal promotes Bcl6 early expression remains unknown....

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Long, Xuehui, Zhang, Le, Zhang, Yang, Min, Min, Lin, Bichun, Chen, Jingjing, Ma, Xiaojie, Zhai, Sulan, Cai, Zhenming, Liu, Yingxia, Lu, Yanlai, Che, Nan, Tan, Wenfeng, Qin, Jun, Wang, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7037247/
https://ncbi.nlm.nih.gov/pubmed/31636135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190832
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