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Histone methyltransferase Nsd2 is required for follicular helper T cell differentiation
Follicular helper T (Tfh) cells provide essential help for humoral immune response. Transcriptional factor Bcl6 is the master regulator for Tfh generation and is induced very early after T cell activation in a CD28-dependent manner, but how CD28 signal promotes Bcl6 early expression remains unknown....
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| Veröffentlicht in: | J Exp Med |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Rockefeller University Press
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037247/ https://ncbi.nlm.nih.gov/pubmed/31636135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190832 |
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