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p73 coordinates with Δ133p53 to promote DNA double-strand break repair
Tumour repressor p53 isoform Δ133p53 is a target gene of p53 and an antagonist of p53-mediated apoptotic activity. We recently demonstrated that Δ133p53 promotes DNA double-strand break (DSB) repair by upregulating transcription of the repair genes RAD51, LIG4 and RAD52 in a p53-independent manner....
Kaydedildi:
| Yayımlandı: | Cell Death Differ |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5988805/ https://ncbi.nlm.nih.gov/pubmed/29511339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0085-8 |
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