p73 coordinates with Δ133p53 to promote DNA double-strand break repair

Tumour repressor p53 isoform Δ133p53 is a target gene of p53 and an antagonist of p53-mediated apoptotic activity. We recently demonstrated that Δ133p53 promotes DNA double-strand break (DSB) repair by upregulating transcription of the repair genes RAD51, LIG4 and RAD52 in a p53-independent manner....

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Foilsithe in:Cell Death Differ
Main Authors: Gong, Hongjian, Zhang, Yuxi, Jiang, Kunpeng, Ye, Shengfan, Chen, Shuming, Zhang, Qinghe, Peng, Jinrong, Chen, Jun
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988805/
https://ncbi.nlm.nih.gov/pubmed/29511339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0085-8
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