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Δ113p53/Δ133p53 converts P53 from a repressor to a promoter of DNA double-stand break repair
In response to DNA damage, p53 (TP53, best known as p53) is quickly activated leading to cell cycle arrest or apoptosis to ensure genomic integrity; however, this represses DNA double-strand break (DSB) repair. Our recent work revealed that Δ113p53/Δ133p53 protein is accumulated at a later stage upo...
Shranjeno v:
| izdano v: | Mol Cell Oncol |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4845190/ https://ncbi.nlm.nih.gov/pubmed/27308550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1033587 |
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