Loss-of-function of p53 isoform Δ113p53 accelerates brain aging in zebrafish

Reactive oxygen species (ROS) stress has been demonstrated as potentially critical for induction and maintenance of cellular senescence, and been considered as a contributing factor in aging and in various neurological disorders including Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (A...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Zhao, Ting, Ye, Shengfan, Tang, Zimu, Guo, Liwei, Ma, Zhipeng, Zhang, Yuxi, Yang, Chun, Peng, Jinrong, Chen, Jun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862496/
https://ncbi.nlm.nih.gov/pubmed/33542214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03438-9
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